|Obama In Favor of Free Speech — In China That Is –
As for free speech on the internet, again Obama’s record at home does not line up with the persona offered in China. It was just a few months ago when the …
Lubbock businessman charged with fraud in alleged ponzi scheme…“Excel Lease Fund Inc.” FBI: Fla. lawyer’s alleged Ponzi scheme likely exceeds $1 billion
Never Follow A Security Guard Into The Back Of The Store By Chris Walters , 6:28 PM on Mon Nov 9 2009, 21532 views Here’s some advice for you, the regular customer who doesn’t shoplift: never go into the back of a store with a security guard, store manager, rent-a-cop, etc.
Braunau’s mayor Gerhard Skiba wants to prevent that happening, but the council does not have the funds to buy it.
The building is currently used by an organisation helping the disabled and has at various times in its history housed a library, bank and technical institute. Some historians have suggested turning the building into a museum.
However Mr Skiba vigorously opposes the idea, saying it would encourage people from all over the world to visit the site.
For the time being, the only reminder of the building’s infamous past is a small memorial dedicated to the victims of the Nazis.
|Thousands of tourists have poured into Berlin to mark the anniversary [Reuters]|
Full story at http://www.sciencemag.org/cgi/content/full/326/5954/788?sa_campaign=Email/sntw/6-November-2009/10.1126/science.326_788
20 Years After the Wall: Why So Few East German Directors?
Full story at http://www.sciencemag.org/cgi/content/full/326/5954/791?sa_campaign=Email/sntw/6-November-2009/10.1126/science.326_791
Video: Fall of the Berlin Wall: The moment the barriers came down ITN NEWS
20 Years After the Wall: Profile: Hübner Family: Big Dreams Come True
Andrew Curry* An East German family of scientists reflects on life before and after 1989. Full story at http://www.sciencemag.org/cgi/content/full/326/5954/792?sa_campaign=Email/sntw/6-November-2009/10.1126/science.326_792
As It Happens
RNA polymerase moves information from the genome (DNA) into pre-messenger RNA (pre-mRNA), from which introns are removed and exons are ligated to make a mature mRNA. To follow the progress of transcription on single genes from start to finish, Wada et al. chose five long human genes whose expression could be switched on by the cytokine tumor necrosis factor–. Putting together snapshots taken at 7.5-min intervals for 3 hours, they documented the waves of RNA synthesized by polymerase, with each molecule of enzyme jumping on at the transcription start site and hopping off over 100 kb away. During each round, upstream introns were excised as the polymerase moved downstream, often before the next intron was reached. Furthermore, it appeared that later rounds of transcription were begun and continued for a few kilobases before being aborted, as if the polymerases were colliding with a checkpoint that kept track of downstream occupancy of the gene. Each wave of transcription traveled at 3 kb m–1, although the accumulation of polymerase at regions bound by the insulator proteins CTCF and cohesion, both of which are involved in chromosome looping, suggested that polymerase may be held up at specific sites.
Proc. Natl. Acad. Sci. U.S.A. 106, 18357 (2009).
Mitch Leslie To keep watch for internal intruders, a cell deploys a cytoplasmic surveillance system that parallels the one detecting menaces outside of its membrane. When infiltrating pathogens trip one of these alarms, the cell retaliates with measures that range from instigating inflammation to committing suicide in a way that alerts other cells to the threat. In turn, microbes have evolved a plethora of countermeasures to disrupt, deceive, and dodge these intracellular weapons. The medical importance of our cells’ internal defenses goes beyond battling pathogens. Errant responses by these alarm systems underlie illnesses such as gout, Crohn’s disease, which is a type of intestinal inflammation, and the lung deterioration provoked by asbestos. Some of what scientists have learned about the mechanisms of such diseases has already made it to the clinic: The discovery that faulty microbial receptors inside the cell are behind several rare but debilitating “fever syndromes” inspired a successful new treatment for those conditions. Researchers have been testing the same drug against gout. Furthermore, scientists have just realized that a chemical long used to boost the effectiveness of vaccines might work by activating one of the cell’s internal tripwires. This insight could lead to the production of better, safer ingredients for future immunizations.
Outfoxing Immune Excess
Immune responses are kept in check by Foxp3-expressing CD4+-regulatory T cells (Tregs) through a variety of mechanisms. Expression of specific transcription factors directs Treg responses into distinct T helper cell lineages; however, the transcription factors that regulate particular helper lineages have not been completely characterized. Chaudhry et al. (p. 986, published online 1 October) show that the transcription factor Stat3, that is required for the initial differentiation of TH17-effector T cells, is also required for Treg cell-mediated suppression of TH17-mediated immune responses. Mice carrying a Treg cell-specific deletion in Stat3 succumb to an intestinal inflammatory disease driven by uncontrolled TH17 responses. Thus, different classes of immune responses can result from the expression of helper lineage–specific transcription factors.
This Week in SCIENCE
November 13 2009, 326 (5955)
The notion of quantum mechanics is that variables are expressed as integer values. In quantum fluids, for instance, vortices are quantized in terms of the polarization and phase shifts observed as multiples of 2, that is, full rotations of each variable around the vortex core. Theoretical work has predicted that in some instances there should be half-quantum vortices, where circumventing the vortex core is characterized by just rotations of the phase and polarization. By observing exciton-polariton condensates Lagoudakis et al. (p. 974) present evidence for the existence of these long-predicted half-quantum vortices.
After reading the above get a load of this….Gandalf Boost for spin-based electronics
ANTI-GRAVITY PROPULSION ENGINE: http://www.youtube.com/watch?v=dSHD9rJWHiE
If you are with me on this, You are good my friends, you get it; and thank you.